SCHEMBL17667102

SCHEMBL17667102

CC1(C)c2ccc(-c3ccc4c(c3)-c3c(c5ccccc5n3-c3ccccc3)C4(C)C)cc2-c2c1c1ccccc1n2-c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ IL1R1 P14778 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ HTT P42858 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ MAPK8 P45983 2/20 0.35
▸ PGR P06401 5/20 0.34
▸ LMNA P02545 2/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ HDAC4 P56524 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ CYP3A4 P08684 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17667135 0.95 L3MBTL1 (0.46) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17667139 0.92 PDE4B (0.37) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17667123 0.90 IL1R1 (0.37) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17710607 0.90 IL1R1 (0.37) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17667129 0.89 IL1R1 (0.36) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL15894370 0.89 IL1R1 (0.38) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17667116 0.88 L3MBTL1 (0.46) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17667126 0.88 PDE4B (0.42) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL17667107 0.88 IL1R1 (0.34) L3MBTL1KDM4EATMIL1R1ALDH1A1
SCHEMBL15894369 0.87 MEN1 (0.37) L3MBTL1KDM4EATMIL1R1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 L3MBTL1 2737/4885KDM4E 922/4885ATM 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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