SCHEMBL17669581

SCHEMBL17669581

O=C(O)Cc1nccn1CC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 6/20 0.52
ALPG P10696 2/20 0.40
PLAA Q9Y263 1/20 0.40
ALPL P05186 1/20 0.39
ESR1 P03372 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CSNK2A2 P19784 2/20 0.38
CSNK2A1 P68400 2/20 0.38
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3587986 0.85 FPR2 (0.49) FPR2ALPGPLAAALPLESR1
SCHEMBL27978839 0.83 SMN1; SMN2 (0.45) FPR2ALPGPLAAALPLESR1
SCHEMBL371254 0.83 ALPG (0.56) FPR2ALPGPLAAALPLESR1
SCHEMBL24201119 0.83 FPR2 (0.48) FPR2ALPGPLAAALPLESR1
SCHEMBL31154491 0.82 FPR2 (0.39) FPR2ALPGPLAAESR1SMN1; SMN2
SCHEMBL28120475 0.81 ESR1 (0.41) FPR2ALPGPLAAALPLESR1
SCHEMBL12037553 0.80 ALPG (0.47) FPR2ALPGPLAAALPLSMN1; SMN2
SCHEMBL10292434 0.79 FPR2 (0.45) FPR2ALPGPLAAALPLESR1
SCHEMBL20724674 0.79 FPR2 (0.45) FPR2ALPGPLAAALPLESR1
SCHEMBL16577159 0.79 FPR2 (0.48) FPR2ALPGPLAAALPLESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3015283-B1 METHOD TO PRODUCE RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2024-05-01 EP disclosed
US-10538647-B2 Rubber composition for tires and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2020-01-21 US disclosed
US-20190048171-A1 RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-02-14 US disclosed
US-10138359-B2 Rubber composition for tires and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-11-27 US disclosed
EP-3015283-A2 RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2016-05-04 EP disclosed
US-20160102193-A1 RUBBER COMPOSITION FOR TIRES AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-04-14 US disclosed