SCHEMBL24201119

SCHEMBL24201119

O=C(O)Cn1ccnc1CI

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 5/20 0.48
CSNK2A2 P19784 2/20 0.40
CSNK2A1 P68400 2/20 0.40
ALPG P10696 2/20 0.39
PLAA Q9Y263 1/20 0.39
ALPL P05186 1/20 0.38
ESR1 P03372 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 2/20 0.36
KMT2A Q03164 1/20 0.36
PTGS2 P35354 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17669581 0.83 FPR2 (0.52) FPR2CSNK2A2CSNK2A1ALPGPLAA
SCHEMBL3587986 0.83 FPR2 (0.49) FPR2CSNK2A2CSNK2A1ALPGPLAA
SCHEMBL371254 0.81 ALPG (0.56) FPR2ALPGPLAAALPLESR1
SCHEMBL12037553 0.79 ALPG (0.47) FPR2ALPGPLAAALPLSMN1; SMN2
SCHEMBL13310633 0.77 FPR2 (0.45) FPR2ALPGPLAAALPLESR1
SCHEMBL10292434 0.77 FPR2 (0.45) FPR2ALPGPLAAALPLESR1
SCHEMBL20724674 0.77 FPR2 (0.45) FPR2CSNK2A2CSNK2A1ALPGPLAA
SCHEMBL16577159 0.77 FPR2 (0.48) FPR2ALPGPLAAALPLESR1
SCHEMBL15501010 0.77 CSNK2A2 (0.46) FPR2CSNK2A2CSNK2A1ESR1SMN1; SMN2
SCHEMBL31590621 0.76 AGTR1 (0.51) FPR2ALPGPLAAALPLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3939972-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2022-01-19 EP disclosed