Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17652726 | 0.95 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDSIGMAR1GALR3 | |
| SCHEMBL17669681 | 0.90 | KMT2A (0.50) | ALDH1A1SMN1; SMN2KCNJ1KMT2A | |
| SCHEMBL17652589 | 0.83 | SIGMAR1 (0.42) | ALDH1A1SIGMAR1HTR7 | |
| SCHEMBL12448363 | 0.76 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDRAB9ATDP1 | |
| SCHEMBL5105861 | 0.76 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDRAB9ATDP1 | |
| SCHEMBL10572672 | 0.76 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2HPGDGALR3NR2F2 | |
| SCHEMBL31195234 | 0.75 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDTDP1CYP19A1 | |
| SCHEMBL31195232 | 0.75 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDTDP1CYP19A1 | |
| SCHEMBL17652975 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2SIGMAR1KMT2A | |
| SCHEMBL17652813 | 0.73 | KMT2A (0.53) | ALDH1A1SMN1; SMN2KCNJ1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941115-B2 | Kinase inhibitors | OXULAR ACQUISITIONS LIMITED (GB) | 2021-03-09 | — | — | US | disclosed |
| US-20190330155-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2019-10-31 | — | — | US | disclosed |
| US-10392346-B2 | Kinase inhibitors | TOPIVERT PHARMA LIMITED (GB) | 2019-08-27 | — | — | US | disclosed |
| US-10125100-B2 | Kinase inhibitors | RESPIVERT LIMITED | 2018-11-13 | — | — | US | disclosed |
| US-20180319748-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| US-20170253563-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2017-09-07 | — | — | US | disclosed |
| US-9751837-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-09-05 | — | — | US | disclosed |
| US-20160102059-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319748-A1 | KINASE INHIBITORS | LYN, SYK, BTK | ALDH1A1 4056/4885SMN1; SMN2 4346/4885HPGD 4567/4885 |
| US-10125100-B2 | Kinase inhibitors | SYK, LYN, SRC | ALDH1A1 4454/4885SMN1; SMN2 3903/4885HPGD 4518/4885 |
| US-20190330155-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 4377/4885SMN1; SMN2 4531/4885HPGD 4040/4885 |
| US-10941115-B2 | Kinase inhibitors | SYK, LYN, BTK | ALDH1A1 4377/4885SMN1; SMN2 4531/4885HPGD 4040/4885 |
| US-20160102059-A1 | KINASE INHIBITORS | SYK, LYN, BTK | ALDH1A1 4380/4885SMN1; SMN2 4459/4885HPGD 4103/4885 |
| US-20170253563-A1 | KINASE INHIBITORS | SYK, LYN, SRC | ALDH1A1 4454/4885SMN1; SMN2 3903/4885HPGD 4518/4885 |
| US-10392346-B2 | Kinase inhibitors | LYN, SYK, BTK | ALDH1A1 4056/4885SMN1; SMN2 4346/4885HPGD 4567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.