Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19459320 | 0.80 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL30526263 | 0.80 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL17671211 | 0.75 | TSHR (0.33) | ALDH1A1POLBHPGDMEN1SCN9A | |
| SCHEMBL17671265 | 0.73 | POLB (0.32) | POLBSCN9A | |
| SCHEMBL19459488 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL3634969 | 0.67 | ALDH1A1 (0.68) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL17671216 | 0.67 | FFAR1 (0.36) | NPC1RAB9A | |
| SCHEMBL1116268 | 0.64 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL19459419 | 0.64 | ALDH1A1 (0.44) | KDM4EALDH1A1L3MBTL1POLBLMNA | |
| SCHEMBL1116275 | 0.64 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016057931-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-04-14 | — | — | WO | disclosed |