Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19459320 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBLMNAL3MBTL1 | |
| SCHEMBL17671264 | 0.80 | KDM4E (0.41) | ALDH1A1KDM4EPOLBLMNAL3MBTL1 | |
| SCHEMBL30526262 | 0.74 | CHRM3 (0.40) | ALDH1A1POLBHPGDSMN1; SMN2MAPT | |
| SCHEMBL30526239 | 0.73 | HTT (0.37) | ALDH1A1POLBHPGDSMN1; SMN2MAPT | |
| SCHEMBL17681704 | 0.73 | HTT (0.37) | ALDH1A1POLBHPGDSMN1; SMN2MAPT | |
| SCHEMBL30526247 | 0.73 | MEN1 (0.37) | HPGDMAPTKMT2AMEN1HTT | |
| SCHEMBL19459272 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KDM4EPOLBHPGDSMN1; SMN2 | |
| SCHEMBL19459427 | 0.70 | PTPN11 (0.38) | MAPTABL1 | |
| SCHEMBL30526243 | 0.68 | MAOB (0.41) | ALDH1A1KDM4EHPGDMAPTKMT2A | |
| SCHEMBL19459549 | 0.67 | MGLL (0.44) | ALDH1A1L3MBTL1KMT2AMEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11724982-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11724982-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | AHR, AFF2, AFF4 | ALDH1A1 778/4885KDM4E 2013/4885POLB 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.