SCHEMBL17674199

SCHEMBL17674199

C[Si](C)(C)OC(=O)CC[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
BLM P54132 1/20 0.46
HBB P68871 1/20 0.46
KMT2A Q03164 1/20 0.46
HIF1A Q16665 1/20 0.46
MAPT P10636 1/20 0.39
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17674232 0.88 ALDH1A1 (0.40) MEN1LMNABLMHBBKMT2A
SCHEMBL17674097 0.86 ALDH1A1 (0.41) MEN1LMNABLMHBBKMT2A
SCHEMBL11601533 0.78 TSHR (0.32) MEN1LMNABLMHBBKMT2A
SCHEMBL4303758 0.77 TSHR (0.45) LMNABLMKMT2AMAPTALDH1A1
SCHEMBL5593734 0.76
SCHEMBL17674260 0.73
SCHEMBL1029123 0.72 LMNA (0.48) MEN1LMNABLMHBBKMT2A
SCHEMBL134075 0.72 TSHR (0.43) LMNAMAPTALDH1A1
SCHEMBL10739007 0.72 TSHR (0.50) MEN1LMNAKMT2AMAPTALDH1A1
Potassium Ion SCHEMBL9416827 0.71 LMNA (0.46) MEN1LMNABLMHBBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
CN-107567464-A For the method for the polydiene and polydiene copolymer that produce cold flow properties reduction 株式会社普利司通 2018-01-09 CN claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
CN-107567464-A For the method for the polydiene and polydiene copolymer that produce cold flow properties reduction 株式会社普利司通 2018-01-09 CN disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed