SCHEMBL17674244

SCHEMBL17674244

C#CC(CC(=O)OC)[N+](=O)[O-]

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17674181 0.82 MAPT (0.39) TSHRHSD17B10MGAMGAASI
SCHEMBL17674044 0.81
SCHEMBL17674046 0.75 ALDH1A1 (0.32) TSHRALDH1A1CYP3A4
SCHEMBL2011018 0.72 TSHR (0.39) TSHRHSD17B10MGAMGAASI
SCHEMBL17673927 0.72 TSHR (0.39) TSHRHSD17B10MGAMGAASI
SCHEMBL17674174 0.69 TSHR (0.36) TSHRHSD17B10MGAMGAASI
SCHEMBL18072538 0.68
SCHEMBL18072529 0.68 MGAM (0.37) TSHRHSD17B10MGAMGAASI
SCHEMBL18072522 0.68 MGAM (0.37) TSHRHSD17B10MGAMGAASI
Hydrochloric Acid SCHEMBL28574258 0.67 LMNA (0.41) TSHRHSD17B10MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed