SCHEMBL17674355

SCHEMBL17674355

C=CCC(C(=O)Oc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
ALOX5 P09917 1/20 0.39
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
THRB P10828 1/20 0.38
CPA1 P15085 1/20 0.37
CYP3A4 P08684 1/20 0.35
ELANE P08246 1/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
KDM4E B2RXH2 2/20 0.35
CASP1 P29466 1/20 0.34
SCN9A Q15858 1/20 0.34
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17673856 0.86 MEN1 (0.38) CYP2C19MEN1KMT2AEGFRERBB2
SCHEMBL17673975 0.83 EGFR (0.40) CYP2C19MEN1KMT2AEGFRERBB2
SCHEMBL17673974 0.83 EGFR (0.40) CYP2C19MEN1KMT2AEGFRERBB2
SCHEMBL5350000 0.80 ATM (0.44) MEN1KMT2AEGFRERBB2ALOX5
SCHEMBL19105309 0.78 CYP2C19 (0.47) CYP2C19MEN1KMT2AATML3MBTL1
SCHEMBL28313029 0.78 CYP2C19 (0.47) CYP2C19MEN1KMT2AATML3MBTL1
SCHEMBL17674327 0.78 ALOX5 (0.40) MEN1KMT2AEGFRERBB2ALOX5
SCHEMBL17674196 0.78 ATM (0.42) MEN1KMT2AEGFRERBB2ALOX5
SCHEMBL17674123 0.77 EGFR (0.43) CYP2C19MEN1KMT2AEGFRERBB2
SCHEMBL17674323 0.77 MEN1 (0.39) MEN1KMT2AEGFRERBB2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed