SCHEMBL5350000

SCHEMBL5350000

CCC(C(=O)Oc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.43
ALOX5 P09917 1/20 0.42
ELANE P08246 2/20 0.41
MAPT P10636 3/20 0.40
SCN9A Q15858 1/20 0.40
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
BCL9 O00512 1/20 0.39
CTNNB1 P35222 1/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 2/20 0.37
MIF P14174 1/20 0.37
FAAH O00519 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17674196 0.88 ATM (0.42) ATML3MBTL1CYP1A2ALOX5ELANE
SCHEMBL30014543 0.83 ZDHHC2 (0.43) L3MBTL1KMT2AALDH1A1FAAH
SCHEMBL17674017 0.82 ATM (0.40) ATML3MBTL1CYP1A2ALOX5ELANE
SCHEMBL17674327 0.81 ALOX5 (0.40) ATML3MBTL1CYP1A2ALOX5ELANE
SCHEMBL17673975 0.81 EGFR (0.40) ATML3MBTL1CYP1A2ALOX5ELANE
SCHEMBL17673974 0.81 EGFR (0.40) ATML3MBTL1CYP1A2ALOX5ELANE
SCHEMBL17674355 0.80 CYP2C19 (0.41) ATML3MBTL1ALOX5ELANESCN9A
SCHEMBL17674323 0.80 MEN1 (0.39) ATML3MBTL1CYP1A2ALOX5ELANE
SCHEMBL9548377 0.79 ALDH1A1 (0.50) L3MBTL1KMT2AALDH1A1TDP1NPC1
SCHEMBL27775170 0.78 LMNA (0.46) ALOX5MEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US claimed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US claimed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP claimed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO claimed
CN-107567464-B Process for producing polydienes and polydiene copolymers having reduced cold flow properties 株式会社普利司通 2020-04-14 CN disclosed
US-10364300-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-07-30 US disclosed
EP-3204429-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2018-09-05 EP disclosed
US-20170247478-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2017-08-31 US disclosed
EP-3204429-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2017-08-16 EP disclosed
WO-2016057388-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-04-14 WO disclosed
CN-100432099-C Transcription factor NOVO NORDISK AS (DK) 2008-11-12 CN disclosed
US-7157262-B2 Lipolytic enzymes NOVOZYMES A/S (DK) 2007-01-02 US disclosed
US-6495357-B1 TO REMOVE LIPID OR FATY STAINS FROM TEXTILES; DETERGENTS NOVOZYME A/S (DK) 2002-12-17 US disclosed
CN-1223663-A Transcription factor NOVO NORDISK AS (DK) 1999-07-21 CN disclosed
EP-0851913-A1 NOVEL LIPOLYTIC ENZYMES NOVO NORDISK A/S (DK) 1998-07-08 EP disclosed
EP-0839186-A1 A MODIFIED ENZYME WITH LIPOLYTIC ACTIVITY NOVO NORDISK A/S (DK) 1998-05-06 EP disclosed
WO-1997007202-A1 NOVEL LIPOLYTIC ENZYMES NOVO NORDISK A/S (DK) 1997-02-27 WO disclosed
WO-1997004079-A1 A MODIFIED ENZYME WITH LIPOLYTIC ACTIVITY NOVO NORDISK A/S (DK) 1997-02-06 WO disclosed
WO-1997004078-A1 A MODIFIED ENZYME WITH LIPOLYTIC ACTIVITY NOVO NORDISK A/S (DK) 1997-02-06 WO disclosed
CN-1055537-A 3, two replacement-2-different  azoles alkane of 5-and different  azoles, its preparation method contain the preparation and the application thereof of this composition HOECHST AG (DE) 1991-10-23 CN disclosed