Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 9/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | FLT4 | P35916 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675210 | 0.88 | BTK (0.67) | BTKEGFRF2KDRPDGFRA | |
| SCHEMBL17675474 | 0.86 | BTK (0.60) | BTKEGFRF2KDRCSF1R | |
| SCHEMBL17675311 | 0.83 | BTK (0.66) | BTKEGFRF2KDRALDH1A1 | |
| SCHEMBL17683838 | 0.81 | EGFR (0.72) | BTKEGFRF2KDRCSF1R | |
| SCHEMBL17683840 | 0.81 | BTK (0.79) | BTKEGFRF2KDRCSF1R | |
| SCHEMBL17675478 | 0.80 | BTK (0.60) | BTKEGFRF2KDRPDGFRA | |
| SCHEMBL17675501 | 0.79 | BTK (0.57) | BTKEGFRF2KDRPDGFRA | |
| SCHEMBL2749120 | 0.78 | ALDH1A1 (0.69) | F2ALDH1A1LMNA | |
| SCHEMBL28689268 | 0.78 | KDR (0.53) | EGFRKDRCSF1RPDGFRBFLT4 | |
| SCHEMBL29385363 | 0.77 | KDR (0.51) | EGFRKDRCSF1RALDH1A1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055982-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS | ACERTA PHARMA B.V. (NL) | 2016-04-14 | — | — | WO | disclosed |