Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21632108 | 0.92 | BCHE (0.47) | ACHEBCHEPOLBRAD52TOP2A | |
| SCHEMBL841682 | 0.84 | MEN1 (0.49) | ACHEBCHEGAARAB9A | |
| SCHEMBL22181050 | 0.84 | ACHE (0.55) | ACHEBCHEPOLBRAD52RAB9A | |
| SCHEMBL202694 | 0.84 | POLB (0.68) | ACHEBCHEPOLBRAD52TOP2A | |
| SCHEMBL211489 | 0.82 | POLB (0.51) | ACHEBCHEPOLBRAD52KDM4E | |
| SCHEMBL8135949 | 0.82 | HTT (0.49) | TOP2ALMNA | |
| SCHEMBL8132565 | 0.82 | MEN1 (0.49) | ACHEBCHEGAARAB9A | |
| SCHEMBL6719555 | 0.82 | KDM4E (0.57) | POLBRAD52TOP2AKDM4EMITF | |
| SCHEMBL17675518 | 0.81 | BCHE (0.48) | ACHEBCHEPOLBRAD52TOP2A | |
| SCHEMBL17675516 | 0.81 | BCHE (0.48) | ACHEBCHEPOLBRAD52TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215189-A1 | POLYMER ADJUVANT | Oxford University Innovation Limited (GB) | 2017-09-13 | — | — | EP | disclosed |
| WO-2016055812-A1 | POLYMER ADJUVANT | ISIS INNOVATION LIMITED (GB) | 2016-04-14 | — | — | WO | disclosed |