SCHEMBL17675752

SCHEMBL17675752

CCN1CCCc2ccc(CNS(=O)(=O)c3cn(C)cn3)cc2C1Cc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 13/20 0.68
LMNA P02545 1/20 0.54
KCNH2 Q12809 1/20 0.51
KMT2A Q03164 4/20 0.48
GAA P10253 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17675757 0.94 SLC6A9 (0.67) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL13827486 0.91 SLC6A9 (0.71) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL13827329 0.81 SLC6A9 (0.67) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL3103622 0.81 SLC6A9 (1.00) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL3111857 0.80 SLC6A9 (0.98) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL13975864 0.79 SLC6A9 (0.78) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL3713045 0.79 SLC6A9 (0.81) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL3103651 0.79 SLC6A9 (0.82) SLC6A9LMNAKCNH2KMT2AGAA
SCHEMBL606106 0.78 SLC6A9 (0.86) SLC6A9LMNAKCNH2KMT2AGAA
Hydrochloric Acid SCHEMBL3108215 0.78 SLC6A9 (0.80) SLC6A9LMNAKCNH2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9309200-B2 Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2016-04-12 US disclosed