Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1134824 | 0.93 | CHRM3 (0.51) | CHRM3CHRM2CHRM1JAK2JAK1 | |
| SCHEMBL302468 | 0.91 | JAK2 (0.48) | CHRM3TDP1CHRM1JAK2JAK1 | |
| SCHEMBL1134849 | 0.90 | CHRM3 (0.49) | CHRM3CHRM2CHRM1 | |
| SCHEMBL121957 | 0.88 | TDP1 (0.53) | CHRM3SUCNR1TDP1F10NTRK1 | |
| SCHEMBL29419144 | 0.88 | TDP1 (0.53) | CHRM3SUCNR1TDP1F10NTRK1 | |
| SCHEMBL13491718 | 0.86 | CHRM3 (0.50) | CHRM3CHRM2CHRM1NTRK1MAPT | |
| SCHEMBL303819 | 0.85 | CHRM3 (0.48) | CHRM3JAK2JAK1NTRK1MAPT | |
| SCHEMBL20875262 | 0.84 | NTRK1 (0.52) | CHRM3TDP1NTRK1MAPT | |
| SCHEMBL1136276 | 0.84 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| SCHEMBL304216 | 0.84 | SSTR2 (0.45) | CHRM3SUCNR1TDP1JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496560-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2012-09-12 | — | — | EP | disclosed |
| EP-2496561-A1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054732-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |
| WO-2011054733-A1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |