Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 13/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767591 | 0.93 | CHRM3 (0.46) | CHRM3CHRM2CHRM1JAK2JAK1 | |
| SCHEMBL302468 | 0.90 | JAK2 (0.48) | CHRM3CHRM1JAK2JAK1DCAF1 | |
| SCHEMBL28496948 | 0.89 | JAK2 (0.45) | CHRM3JAK2JAK1DCAF1 | |
| SCHEMBL1134849 | 0.89 | CHRM3 (0.49) | CHRM3CHRM2CHRM1TAS1R3TAS1R1 | |
| SCHEMBL13491718 | 0.89 | CHRM3 (0.50) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1136276 | 0.88 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1900167 | 0.87 | JAK2 (0.44) | CHRM3JAK2JAK1DCAF1 | |
| SCHEMBL68043 | 0.87 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| SCHEMBL29445383 | 0.87 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 | |
| SCHEMBL29349968 | 0.87 | CHRM3 (0.51) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285779-B1 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-03-27 | — | — | EP | claimed |
| US-8350046-B2 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-01-08 | — | — | US | claimed |
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | BASF SE | 2011-03-03 | — | — | US | claimed |
| EP-2300417-B1 | PROCESS FOR PREPARING 2-(AMINOMETHYLIDENE)-4,4-DIFLUORO-3-OXOBUTYRIC ESTERS | BASF SE (DE) | 2015-07-22 | — | — | EP | disclosed |
| EP-2496560-B1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2015-04-22 | — | — | EP | disclosed |
| EP-2288597-B1 | METHOD FOR PREPARING 1,3,4-SUBSTITUTED PYRAZOL COMPOUNDS | BASF SE (DE) | 2014-10-29 | — | — | EP | disclosed |
| EP-2496561-B1 | PROCESS FOR PREPARING AMINALE AND THEIR USE FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-8598222-B2 | Method for preparing 1,3,4-substituted pyrazol compounds | BASF SE (DE) | 2013-12-03 | — | — | US | disclosed |
| US-8592578-B2 | Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters | BASF SE (DE) | 2013-11-26 | — | — | US | disclosed |
| US-8586750-B2 | Method for the production of halogen-substituted 2-(aminomethylidene)-3-oxobutyric acid esters | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| EP-2285779-B1 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-03-27 | — | — | EP | disclosed |
| US-20110040096-A1 | Method for the Production of Halogen-Substituted 2-(aminomethylidene)-3-oxobutyric Acid Esters | BASF SE (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20100184994-A1 | Method for Producing Difluoromethyl-Substituted Pyrazole Compounds | BASF SE (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2158185-A2 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | Basf Se (DE) | 2010-03-03 | — | — | EP | disclosed |
| WO-2009135808-A2 | METHOD FOR PREPARING 1,3,4-SUBSTITUTED PYRAZOL COMPOUNDS | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009135860-A1 | METHOD FOR MANUFACTURING ARYL CARBOXAMIDES | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009133178-A1 | PROCESS FOR PREPARING 2-(AMINOMETHYLIDENE)-4,4-DIFLUORO-3-OXOBUTYRIC ESTERS | BASF SE (DE) | 2009-11-05 | — | — | WO | disclosed |
| WO-2009133179-A2 | METHOD FOR THE PRODUCTION OF HALOGEN-SUBSTITUTED 2-(AMINOMETHYLIDENE)-3- OXOBUTYRIC ACID ESTERS | BASF SE (DE) | 2009-11-05 | — | — | WO | disclosed |
| WO-2008152138-A2 | METHOD FOR PRODUCING DIFLUOROMETHYL-SUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008014905-A2 | 3-DIFLUOROMETHYLPYRAZOLYLCARBOXANILIDES | BAYER CROPSCIENCE AG (DE) | 2008-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 | CHRM3 910/4885CHRM2 1036/4885CHRM1 957/4885 |
| US-20100184994-A1 | Method for Producing Difluoromethyl-Substituted Pyrazole Compounds | NR4A1, NR4A3, NR3C1 | CHRM3 183/4885CHRM2 292/4885CHRM1 120/4885 |
| US-20110040096-A1 | Method for the Production of Halogen-Substituted 2-(aminomethylidene)-3-oxobutyric Acid Esters | AADAC, CBR3, AOC3 | CHRM3 121/4885CHRM2 141/4885CHRM1 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.