SCHEMBL302468

SCHEMBL302468

Cn1cc(C(=O)Nc2ccccc2-c2cccc(Cl)c2)c(C(F)F)n1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 7/20 0.48
JAK1 P23458 1/20 0.48
CHRM3 P20309 4/20 0.47
DCAF1 Q9Y4B6 1/20 0.44
POLB P06746 2/20 0.44
TP53 P04637 1/20 0.44
MAPT P10636 2/20 0.43
CHRM1 P11229 1/20 0.43
CYP3A4 P08684 1/20 0.43
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
ATM Q13315 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304216 0.92 SSTR2 (0.45) JAK2JAK1CHRM3POLBTP53
SCHEMBL1767591 0.91 CHRM3 (0.46) JAK2JAK1CHRM3MAPTCHRM1
SCHEMBL1134824 0.90 CHRM3 (0.51) JAK2JAK1CHRM3DCAF1CHRM1
SCHEMBL303819 0.90 CHRM3 (0.48) JAK2JAK1CHRM3POLBTP53
SCHEMBL4456706 0.89 CHRM3 (0.51) JAK2JAK1CHRM3POLBTP53
SCHEMBL28496948 0.89 JAK2 (0.45) JAK2JAK1CHRM3DCAF1POLB
SCHEMBL29419144 0.89 TDP1 (0.53) CHRM3POLBTP53MAPTALDH1A1
SCHEMBL121957 0.89 TDP1 (0.53) CHRM3POLBTP53MAPTALDH1A1
SCHEMBL1085490 0.88 ALDH1A1 (0.50) POLBMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL567351 0.88 CHRM3 (0.47) JAK2JAK1CHRM3POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2489262-B1 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2018-11-14 EP claimed
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES BASF SE (DE) 2015-03-19 US claimed
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2014-06-26 US claimed
US-20130267414-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-10-10 US claimed
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 US claimed
EP-2489263-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2489264-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a carboxamide fungicide BASF SE (DE) 2012-08-22 EP claimed
EP-2489262-A2 Pesticidal mixtures comprising an anthranilamide insecticide and a fungicide BASF SE (DE) 2012-08-22 EP claimed
JP-2012500824-A 2012-01-12 JP claimed
JP-2011527306-A 2011-10-27 JP claimed
EP-2091330-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2009-08-26 EP claimed
EP-2091331-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2009-08-26 EP claimed
WO-2009065834-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2009-05-28 WO claimed
WO-2009062905-A1 PESTICIDAL MIXTURES COMPRISING CYANOSULFOXIMINE COMPOUNDS BASF SE (DE) 2009-05-22 WO claimed
WO-2009063076-A2 FUNGICIDAL MIXTURES III BASF SE (DE) 2009-05-22 WO claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
WO-2009063074-A2 FUNGICIDAL MIXTURES I BASF SE (DE) 2009-05-22 WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 WO claimed
WO-2008034785-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed
WO-2008034787-A2 PESTICIDAL MIXTURES COMPRISING AN ANTHRANILAMIDE INSECTICIDE AND A FUNGICIDE BASF SE (DE) 2008-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267414-A1 PESTICIDAL MIXTURES AADAC, CTRL, AAAS JAK2 3540/4885JAK1 3828/4885CHRM3 1321/4885
US-20140179518-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CPN1, SRM, STS JAK2 1531/4885JAK1 761/4885CHRM3 153/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP JAK2 4698/4885JAK1 4445/4885CHRM3 256/4885
US-20150080215-A1 TERNARY PESTICIDAL MIXTURES AADAC, AS3MT, DDT JAK2 2618/4885JAK1 2120/4885CHRM3 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.