SCHEMBL17677032

SCHEMBL17677032

CC1(C)c2ccccc2-c2c1c1cc(-n3c4ccccc4c4ccccc43)ccc1n2-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ HDAC4 P56524 1/20 0.37
▸ IL1R1 P14778 1/20 0.35
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ GSK3B P49841 1/20 0.32
▸ RAC2 P15153 1/20 0.32
▸ RAC3 P60763 1/20 0.32
▸ CDC42 P60953 1/20 0.32
▸ RAC1 P63000 1/20 0.32
▸ PGR P06401 3/20 0.32
▸ EDNRA P25101 2/20 0.31
▸ EDNRB P24530 1/20 0.31
▸ AKR1C4 P17516 1/20 0.31
▸ AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17677089 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL17677012 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL15860855 0.92 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL17689930 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL15860849 0.91 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL17677040 0.90 KDM4E (0.35) L3MBTL1KDM4EATMPGR
SCHEMBL17689978 0.89 IL1R1 (0.37) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL17689954 0.87 L3MBTL1 (0.44) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL15860864 0.86 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4IL1R1
SCHEMBL15860730 0.85 L3MBTL1 (0.36) L3MBTL1KDM4EATMHDAC4IL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3006426-B1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-01-09 — — EP disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-9985216-B2 Indenoindole derivative and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2018-05-29 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO., LTD. (JP) 2016-05-05 — — US disclosed
EP-3006426-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2016-04-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160126468-A1 INDENOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDO2, SLCO2B1, IDO1 L3MBTL1 2737/4885KDM4E 922/4885ATM 3172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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