Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18488791 | 0.76 | JAK2 (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL18488794 | 0.76 | JAK2 (0.36) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL18231224 | 0.72 | CYP2D6 (0.32) | — | |
| SCHEMBL14155705 | 0.72 | — | — | |
| SCHEMBL12575131 | 0.71 | NAAA (0.37) | — | |
| SCHEMBL796492 | 0.68 | NPC1 (0.38) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL14359726 | 0.67 | SCN9A (0.34) | — | |
| SCHEMBL18488808 | 0.67 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL18488807 | 0.67 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL17430832 | 0.67 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162429-B1 | HALOGEN-CONTAINING ORGANOSULFUR COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2016-04-13 | — | — | EP | disclosed |