Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273750 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL17677461 | 0.84 | HPGD (0.34) | KMT2AMEN1KDM4EHPGDALDH1A1 | |
| SCHEMBL16910890 | 0.76 | ALDH1A1 (0.31) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL16910891 | 0.76 | ALDH1A1 (0.31) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL16920760 | 0.76 | ALDH1A1 (0.31) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL17600113 | 0.74 | KDM4E (0.34) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17226730 | 0.72 | HIF1A (0.39) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL18831331 | 0.71 | CYP1A2 (0.32) | — | |
| SCHEMBL17600071 | 0.71 | PTGER1 (0.35) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17600282 | 0.70 | KDM4E (0.34) | SMN1; SMN2KMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | Sumitomo Chemical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |