Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17677486 | 0.84 | SMN1; SMN2 (0.33) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL16273662 | 0.83 | HPGD (0.36) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL18831331 | 0.79 | CYP1A2 (0.32) | CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL16273663 | 0.78 | MAPT (0.36) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL17600113 | 0.77 | KDM4E (0.34) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL16910708 | 0.74 | MEN1 (0.34) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL16910940 | 0.72 | SENP2 (0.38) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL16273737 | 0.72 | HPGD (0.36) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL16273669 | 0.72 | FFAR1 (0.32) | HPGDMEN1CYP1A2KMT2AMAPT | |
| SCHEMBL18831451 | 0.71 | NR1H4 (0.32) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-A1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | Sumitomo Chemical Company Limited (JP) | 2016-04-13 | — | — | EP | disclosed |