SCHEMBL176785

SCHEMBL176785

Cc1c(Cl)cc(N)cc1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.44
HSD17B10 Q99714 4/20 0.44
RECQL P46063 3/20 0.44
CYP3A4 P08684 3/20 0.44
TSHR P16473 3/20 0.44
CASP1 P29466 2/20 0.44
THRB P10828 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
TDP1 Q9NUW8 4/20 0.43
CASP7 P55210 1/20 0.43
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
CASP6 P55212 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ELAVL1 Q15717 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11337312 0.86 ALDH1A1 (0.50) ALDH1A1HSD17B10RECQLTSHRCASP1
SCHEMBL28138578 0.85 ALDH1A1 (0.61) ALDH1A1HSD17B10RECQLCYP3A4TSHR
SCHEMBL4003250 0.82 CA1 (0.47) ALDH1A1HSD17B10RECQLCYP3A4TSHR
SCHEMBL10394272 0.82 ALDH1A1 (0.54) ALDH1A1HSD17B10RECQLCYP3A4TSHR
SCHEMBL23566465 0.80 CA1 (0.46) ALDH1A1HSD17B10RECQLCYP3A4TSHR
SCHEMBL9680119 0.80 TDP1 (0.47) ALDH1A1HSD17B10RECQLCYP3A4TSHR
SCHEMBL11692848 0.80 ALDH1A1 (0.47) ALDH1A1HSD17B10RECQLCYP3A4TSHR
SCHEMBL1365040 0.80 ALDH1A1 (0.46) ALDH1A1HSD17B10RECQLTSHRCASP1
SCHEMBL13277835 0.78 CA1 (0.44) ALDH1A1HSD17B10RECQLCYP3A4TSHR
Hydrochloric Acid SCHEMBL28326253 0.78 CASR (0.41) ALDH1A1RECQLTSHRTHRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49569-E1 Alkylamine derivative EA PHARMA CO., LTD. (JP) 2023-07-04 US disclosed
EP-2546231-B1 ALKYLAMINE DERIVATIVE EA PHARMA CO LTD (JP) 2018-11-07 EP disclosed
CN-103951615-B Alkylamine derivative EA制药株式会社 2017-04-12 CN disclosed
US-9561216-B2 Alkylamine derivative EA PHARMA CO., LTD. (JP) 2017-02-07 US disclosed
US-20160101091-A1 ALKYLAMINE DERIVATIVE AJINOMOTO CO., INC. (JP) 2016-04-14 US disclosed
CN-103980309-B Casr agonist AJINOMOTO K. K. (JP) 2016-04-06 CN disclosed
EP-2345636-B1 CASR AGONIST AJINOMOTO KK (JP) 2016-03-30 EP disclosed
US-9253997-B2 Alkylamine derivative AJINOMOTO CO., INC. (JP) 2016-02-09 US disclosed
US-9174932-B2 CaSR agonists AJINOMOTO CO., INC. (JP) 2015-11-03 US disclosed
US-9150505-B2 Prophylactic or therapeutic agent for diabetes or obesity AJINOMOTO CO., INC. (JP) 2015-10-06 US disclosed
US-4810302-A STORAGE STABLE MIXTURES TOYO INK MANUFACTURING CO., LTD. (JP) 1989-03-07 US disclosed
US-4782140-A Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge CIBA-GIEGY CORPORATION (US) 1988-11-01 US disclosed
EP-0144766-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1988-10-05 EP disclosed
US-4754023-A Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member CIBA-GEIGY CORPORATION (US) 1988-06-28 US disclosed
EP-0159292-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
EP-0159292-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-23 EP disclosed
EP-0144766-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0079562-B1 WATER-SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-05-29 EP disclosed
EP-0079562-A1 Water-soluble disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-25 EP disclosed
US-4014866-A FOR SURFACE COATINGS, PRINTING INKS AND RESINS BASF AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160101091-A1 ALKYLAMINE DERIVATIVE CASR, TAAR5, TAAR1 ALDH1A1 2451/4885HSD17B10 2174/4885RECQL 3095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.