Piperitone

Piperitone

SCHEMBL1767896

CC1(C)C2CC=C(C=O)C1C2.CC1=CC(=O)C(C(C)C)CC1.CC1=CC(=O)C2CC1C2(C)C

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.37
TSHR P16473 1/20 0.37
ALOX12 P18054 2/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperitone SCHEMBL13728035 0.92 ALOX12 (0.39) MAPK1TSHRALOX12ALDH1A1KDM4E
Verbenone SCHEMBL4254806 0.85 MAPK1 (0.50) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL1300746 0.71 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL5391946 0.71 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL228374 0.71 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
(-)-Piperitone SCHEMBL3508682 0.68 TLR4 (0.40)
Piperitone SCHEMBL111913 0.68 TLR4 (0.40)
(-)-Piperitone SCHEMBL1248697 0.68 TLR4 (0.40)
Levoverbenone SCHEMBL21046 0.67 TSHR (0.41) MAPK1TSHR
Verbenone SCHEMBL12914978 0.67 TSHR (0.41) MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2721041-A1 NEW COUPLING AGENTS FOR ELASTOMER COMPOSITIONS Rhodia (China) Co., Ltd. (CN) 2014-04-23 EP disclosed
WO-2012146198-A1 NEW COUPLING AGENTS FOR ELASTOMER COMPOSITIONS RHODIA (CHINA) CO., LTD. (CN) 2012-11-01 WO disclosed
EP-2493901-A1 CONJUGATED DIENE PHOSPHINATE COMPOUNDS, PREPARATION METHOD AND USE THEREOF Rhodia (China) Co., Ltd. (CN) 2012-09-05 EP disclosed
EP-2493903-A1 METHOD FOR PREPARING CONJUGATED DIENE PHOSPHONATE COMPOUNDS Rhodia (China) Co., Ltd. (CN) 2012-09-05 EP disclosed
WO-2011050537-A1 CONJUGATED DIENE PHOSPHINATE COMPOUNDS, PREPARATION METHOD AND USE THEREOF RHODIA (CHINA) CO., LTD. (CN) 2011-05-05 WO disclosed
WO-2011050533-A1 METHOD FOR PREPARING CONJUGATED DIENE PHOSPHONATE COMPOUNDS RHODIA (CHINA) CO., LTD. (CN) 2011-05-05 WO disclosed