SCHEMBL228374

SCHEMBL228374

CC1(C)C2CC=C(C=O)C1C2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.55
TSHR P16473 2/20 0.55
ALOX12 P18054 4/20 0.52
ALDH1A1 P00352 5/20 0.51
KDM4E B2RXH2 3/20 0.51
LMNA P02545 3/20 0.46
HPGD P15428 1/20 0.45
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
RECQL P46063 1/20 0.45
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
CXCR3 P49682 2/20 0.38
TRPA1 O75762 1/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5391946 1.00 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL1300746 1.00 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
Verbenone SCHEMBL4254806 0.83 MAPK1 (0.50) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL5297079 0.81 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL11074361 0.81 MAPK1 (0.55) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL18339258 0.78 MAPK1 (0.52) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL18339257 0.78 MAPK1 (0.52) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL7743417 0.77 ALOX12 (0.42) MAPK1TSHRALOX12ALDH1A1KDM4E
Piperitone SCHEMBL13728035 0.77 ALOX12 (0.39) MAPK1TSHRALOX12ALDH1A1KDM4E
SCHEMBL14321805 0.74 MAPK1 (0.47) MAPK1TSHRALOX12ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352444-A1 Antimicrobial mixtures SYMRISE AG (DE) 2025-11-20 US claimed
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
US-12378173-B2 Method of production of bicyclic hydrocarbons CleanJoule, Inc. (US) 2025-08-05 US claimed
US-20250197326-A1 METHOD OF PRODUCTION OF BICYCLIC HYDROCARBONS CleanJoule, Inc. (US) 2025-06-19 US claimed
EP-4525822-A1 ANTIMICROBIAL MIXTURES Symrise AG (DE) 2025-03-26 EP claimed
EP-4096618-B1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2025-01-29 EP claimed
CN-119255781-A Antimicrobial mixtures 西姆莱斯股份公司 2025-01-03 CN claimed
CN-119118895-A Method for synthesizing 3-fluoropyrrole compound by palladium catalytic defluorination and cyclization 南京工业大学 2024-12-13 CN claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 EP claimed
CN-119080711-A Preparation method and application of myrtenyl-1, 3, 4-oxadiazole formylhydrazine compound 南京林业大学 2024-12-06 CN claimed
US-5079000-A Fungicides, bactericides, insecticides useful for stored fruits and vegetables, natural products KURITA WATER INDUSTRIES LTD. (JP) 1992-01-07 US claimed
EP-0247595-B1 NEW AZAPHOSPHOLONES AND USE THEREOF Studiengesellschaft Kohle mbH (DE) 1992-01-02 EP claimed
US-4948597-A WITH MYRTENAL OR THE CORRESPONDING METHYL KETONE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1990-08-14 US claimed
US-4900866-A Azaphospholenes STUDIENGESELLSCHAFT KOHLE MBH (DE) 1990-02-13 US claimed
US-4774076-A DENTIFRICES, MOUTHWASHES LION CORPORATION (JP) 1988-09-27 US claimed
EP-0150293-B1 SUBSTRATE FOR OPTICAL RECORDING MEDIA SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-08-17 EP claimed
US-4743409-A INJECTION MOLDING POLYVINYL ACETAL RESINS SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-05-10 US claimed
EP-0247595-A2 New azaphospholones and use thereof Studiengesellschaft Kohle mbH (DE) 1987-12-02 EP claimed
US-4649044-A DISCOLORATION INHIBITION LION CORPORATION (JP) 1987-03-10 US claimed
EP-0150293-A1 Substrate for optical recording media SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1985-08-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250352444-A1 Antimicrobial mixtures LRBA, MGLL, TAS2R50 MAPK1 4274/4885TSHR 3863/4885ALOX12 185/4885
US-20250197326-A1 METHOD OF PRODUCTION OF BICYCLIC HYDROCARBONS DHPS, CYP2E1, CYP11B2 MAPK1 3325/4885TSHR 3387/4885ALOX12 76/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 MAPK1 4320/4885TSHR 2980/4885ALOX12 88/4885
US-12378173-B2 Method of production of bicyclic hydrocarbons DHPS, CYP2E1, CYP11B2 MAPK1 3325/4885TSHR 3387/4885ALOX12 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.