Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19272946 | 0.83 | PIK3CD (0.36) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL25045013 | 0.82 | CA1 (0.43) | SMN1; SMN2PIK3CDCHRM2CHRM4CHRM5 | |
| SCHEMBL27615004 | 0.77 | ACE (0.37) | SMN1; SMN2PIK3CDCHRM2CHRM4CHRM5 | |
| Methyl Alcohol SCHEMBL27615034 | 0.76 | ACE (0.36) | SMN1; SMN2PIK3CDCHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL28093485 | 0.72 | ACHE (0.58) | — | |
| Hydrochloric Acid SCHEMBL8129116 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12066432 | 0.71 | — | — | |
| SCHEMBL6629045 | 0.71 | — | — | |
| SCHEMBL14074335 | 0.70 | — | — | |
| SCHEMBL11619916 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134661-A1 | Process for the Preparation of (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LAB LTD (IN) | 2018-05-17 | — | — | US | disclosed |
| US-9951012-B2 | Process for the preparation of (3R,4R)-(1-benzyl-4-methylpiperidin-3-yl)-methylamine | UNICHEM LABORATORIES LIMITED (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20180037551-A1 | Process for the Preparation of (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LAB LTD (IN) | 2018-02-08 | — | — | US | disclosed |
| US-20170240510-A1 | PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LAB LTD (IN) | 2017-08-24 | — | — | US | disclosed |
| US-20160102057-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | UNICHEM LABORATORIES LIMITED (IN) | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037551-A1 | Process for the Preparation of (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | KDM4D, KDM4A, KDM4C | SMN1; SMN2 4090/4885PIK3CD 1951/4885CHRM2 200/4885 |
| US-20180134661-A1 | Process for the Preparation of (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | KDM4D, KDM4A, KDM4C | SMN1; SMN2 4090/4885PIK3CD 1951/4885CHRM2 200/4885 |
| US-20160102057-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | KDM4D, KDM4A, KDM4C | SMN1; SMN2 4573/4885PIK3CD 1923/4885CHRM2 200/4885 |
| US-20170240510-A1 | PROCESS FOR THE PREPARATION OF (3R,4R)-(1-BENZYL-4-METHYLPIPERIDIN-3-YL)-METHYLAMINE | KDM4D, KDM4A, KDM4C | SMN1; SMN2 4090/4885PIK3CD 1951/4885CHRM2 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.