Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27615034 | 0.98 | ACE (0.36) | ACEHSD17B10HTTSMN1; SMN2ITGB3 | |
| SCHEMBL17679244 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL835266 | 0.72 | HTT (0.50) | HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL27856183 | 0.71 | LMNA (0.44) | ACEHSD17B10 | |
| Hydrochloric Acid SCHEMBL1375997 | 0.71 | HTT (0.49) | HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL6548967 | 0.70 | ACE (0.59) | ACECHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28280267 | 0.70 | HSD17B10 (0.39) | ACEHSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28093485 | 0.70 | ACHE (0.58) | — | |
| SCHEMBL21675650 | 0.69 | HSD17B10 (0.45) | HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL2557014 | 0.69 | L3MBTL1 (0.42) | HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101353321-A | 3-amino-piperadine derivatives and methods of manufacture | PFIZER (US) | 2009-01-28 | — | — | CN | disclosed |
| CN-1726192-A | 3-amino-piperidine derivatives and process for preparing same | PFIZER (US) | 2006-01-25 | — | — | CN | disclosed |