Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 8/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18082187 | 0.85 | SMYD2 (0.37) | SMYD2SMN1; SMN2CYP3A4HTTPPARD | |
| SCHEMBL18082177 | 0.85 | SMYD2 (0.38) | SMYD2SMN1; SMN2CYP3A4HTTPPARD | |
| SCHEMBL18082175 | 0.84 | SMYD2 (0.35) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL29627016 | 0.84 | FAAH (0.49) | TDP1FAAHSMYD2SMN1; SMN2CYP3A4 | |
| SCHEMBL32687598 | 0.81 | TDP1 (0.59) | TDP1PIN1MEN1KMT2AALDH1A1 | |
| SCHEMBL18082178 | 0.80 | SMYD2 (0.36) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL19758899 | 0.80 | SMYD2 (0.36) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL5026273 | 0.80 | SMYD2 (0.38) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL5026278 | 0.80 | SMYD2 (0.38) | SMYD2SMN1; SMN2CYP3A4HTT | |
| SCHEMBL29627013 | 0.80 | PPARD (0.37) | SMYD2SMN1; SMN2CYP3A4HTTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016057660-A1 | PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MITOBRIDGE, INC. (US) | 2016-04-14 | — | — | WO | disclosed |