SCHEMBL29627016

SCHEMBL29627016

CCOC(=O)CC(C)CCCCCCCO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.49
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
SMYD2 Q9NRG4 1/20 0.34
LTA4H P09960 1/20 0.34
TBXAS1 P24557 2/20 0.33
CYP3A4 P08684 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PIN1 Q13526 1/20 0.33
F2 P00734 1/20 0.33
MAPT P10636 1/20 0.33
HSD11B1 P28845 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29627013 0.87 PPARD (0.37) SMYD2CYP3A4HTTSMN1; SMN2
SCHEMBL29113320 0.87 FAAH (0.43) FAAHTSHRALDH1A1TDP1CYP3A4
SCHEMBL29113314 0.87 FAAH (0.43) FAAHTSHRALDH1A1TDP1CYP3A4
SCHEMBL29113315 0.87 FAAH (0.43) FAAHTSHRALDH1A1TDP1CYP3A4
SCHEMBL29113331 0.87 FAAH (0.43) FAAHTSHRALDH1A1TDP1CYP3A4
SCHEMBL29113317 0.87 FAAH (0.43) FAAHTSHRALDH1A1TDP1CYP3A4
SCHEMBL19582827 0.86 FAAH (0.36) FAAHALDH1A1SMYD2CYP3A4HTT
SCHEMBL17679352 0.84 TDP1 (0.37) FAAHALDH1A1TDP1SMYD2CYP3A4
SCHEMBL29626940 0.82 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2
SCHEMBL16436925 0.81 TOP2A (0.44) FAAHALDH1A1LTA4HTBXAS1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2026-04-16 US disclosed
US-20250352510-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-11-20 US disclosed
US-20250213522-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-07-03 US disclosed
EP-4578865-A2 LYMPH DIRECTING PRODRUGS Monash University (AU) 2025-07-02 EP disclosed
EP-3180349-B1 LYMPH DIRECTING PRODRUGS AND THERAPEUTIC USES THEREOF UNIV MONASH (AU) 2025-03-12 EP disclosed
CN-117164657-A Prodrugs of directed lymphatics 莫纳什大学 2023-12-05 CN disclosed
CN-117088931-A Prodrugs of directed lymphatics 莫纳什大学 2023-11-21 CN disclosed
CN-106715456-B Prodrugs of directed lymphatics 莫纳什大学 2023-08-29 CN disclosed
US-20220211664-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2022-07-07 US disclosed
US-11311512-B2 Lymph directing prodrugs MONASH UNIVERSITY (AU) 2022-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211664-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN FAAH 748/4885TSHR 3045/4885ALDH1A1 1056/4885
US-11311512-B2 Lymph directing prodrugs LTA, ABCB11, LYN FAAH 748/4885TSHR 3045/4885ALDH1A1 1056/4885
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MALT1, CES1, LIPA FAAH 94/4885TSHR 1545/4885ALDH1A1 1086/4885
US-20250213522-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN FAAH 748/4885TSHR 3045/4885ALDH1A1 1056/4885
US-20250352510-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN FAAH 748/4885TSHR 3045/4885ALDH1A1 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.