Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17679392 | 0.81 | KMT2A (0.48) | ALDH1A1LMNACYP3A4TK1ADRB2 | |
| SCHEMBL17679376 | 0.81 | KMT2A (0.50) | MAPK1HIF1AALDH1A1LMNACYP3A4 | |
| SCHEMBL16254156 | 0.78 | LMNA (0.46) | MAPK1ALDH1A1LMNACYP3A4TK1 | |
| SCHEMBL17679373 | 0.77 | ALDH1A1 (0.49) | MAPK1HIF1AALDH1A1LMNACYP3A4 | |
| SCHEMBL17886498 | 0.76 | ALDH1A1 (0.44) | MAPK1HIF1AALDH1A1LMNACYP3A4 | |
| Benzene SCHEMBL28207781 | 0.74 | CYP3A4 (0.69) | MAPK1HIF1AALDH1A1LMNACYP3A4 | |
| SCHEMBL21007 | 0.74 | CYP3A4 (0.69) | MAPK1HIF1AALDH1A1LMNACYP3A4 | |
| SCHEMBL28343462 | 0.74 | CYP3A4 (0.69) | MAPK1HIF1AALDH1A1LMNACYP3A4 | |
| SCHEMBL8522570 | 0.73 | TDP1 (0.61) | MAPK1HIF1AALDH1A1LMNATK1 | |
| SCHEMBL8522569 | 0.73 | TDP1 (0.61) | MAPK1HIF1AALDH1A1LMNATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | ZFR, ZDHHC7, ORC3 | MAPK1 4664/4885HIF1A 4488/4885ALDH1A1 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.