Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17673192 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL19518355 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL17680928 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL17680841 | 0.77 | CYP1A2 (0.44) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL11201804 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL17673169 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL19518273 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL11195406 | 0.71 | MEN1 (0.47) | ALDH1A1MAPTMEN1KMT2APKM | |
| SCHEMBL19518324 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL17673257 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |