Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17673191 | 0.84 | CYP1A2 (0.47) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL19518237 | 0.84 | CYP1A2 (0.47) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL17673293 | 0.81 | ALDH1A1 (0.45) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL17673278 | 0.81 | ALDH1A1 (0.45) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL17680928 | 0.80 | ALDH1A1 (0.43) | CYP1A2POLBCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL17680858 | 0.77 | KMT2A (0.38) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL17680663 | 0.77 | PIM1 (0.38) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL17680666 | 0.77 | ALDH1A1 (0.46) | CYP1A2TSHRPOLBCYP3A4CYP2C19 | |
| SCHEMBL17680888 | 0.76 | L3MBTL1 (0.41) | CYP1A2POLBCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL17244016 | 0.74 | CYP1A2 (0.44) | CYP1A2TSHRPOLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016055028-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2016-04-14 | — | — | WO | disclosed |