SCHEMBL176813

SCHEMBL176813

N[C@@H](CCC(=O)Nc1ccccc1)C(=O)O

nearest known ligand 0.91

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 13/20 0.91
L3MBTL1 Q9Y468 1/20 0.59
SLC1A3 P43003 2/20 0.58
SLC1A2 P43004 2/20 0.58
SLC1A1 P43005 2/20 0.58
MAPT P10636 2/20 0.54
HTT P42858 1/20 0.54
ALDH1A1 P00352 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2522620 1.00 LTA4H (0.91) LTA4HL3MBTL1SLC1A3SLC1A2SLC1A1
SCHEMBL20238887 0.95 LTA4H (1.00) LTA4HL3MBTL1SLC1A3SLC1A2SLC1A1
SCHEMBL20238889 0.95 LTA4H (1.00) LTA4HL3MBTL1SLC1A3SLC1A2SLC1A1
SCHEMBL21690025 0.90 LTA4H (0.75) LTA4HL3MBTL1SLC1A3SLC1A2SLC1A1
SCHEMBL10882882 0.88 LTA4H (0.72) LTA4HL3MBTL1MAPTHTT
SCHEMBL10879524 0.88 LTA4H (0.72) LTA4HL3MBTL1MAPTHTT
SCHEMBL24032787 0.87 LTA4H (0.75) LTA4HSLC1A3SLC1A2SLC1A1
SCHEMBL3503717 0.87 LTA4H (0.75) LTA4HSLC1A3SLC1A2SLC1A1
SCHEMBL3503714 0.87 LTA4H (0.75) LTA4HSLC1A3SLC1A2SLC1A1
SCHEMBL29398310 0.87 LTA4H (0.75) LTA4HSLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252728-B2 Systems and methods for measuring liver enzyme levels in blood NOVA BIOMEDICAL CORPORATION (US) 2025-03-18 US claimed
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC (JP) 2026-04-09 US disclosed
US-12528808-B2 Therapy for erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-01-20 US disclosed
EP-4594336-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PeptiDream Inc. (JP) 2025-08-06 EP disclosed
US-20250171824-A1 Analyte Sensor Strip for Measuring Liver Enzyme Levels NOVA BIOMEDICAL CORPORATION 2025-05-29 US disclosed
US-12252728-B2 Systems and methods for measuring liver enzyme levels in blood NOVA BIOMEDICAL CORPORATION (US) 2025-03-18 US disclosed
CN-114096250-B Therapies for erythropoiesis protoporphyria (EPP) and X-linked protoporphyria (XLP) 匹兹堡大学 联邦高等教育系统 2025-01-14 CN disclosed
CN-119306640-A Gamma-glutamyl transpeptidase detection substrate and preparation method and application thereof 英科新创(厦门)科技股份有限公司 2025-01-14 CN disclosed
US-20240200049-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR MAKING POLYPEPTIDES WITH MANY INSTANCES OF NONSTANDARD AMINO ACIDS YALE UNIVERSITY 2024-06-20 US disclosed
WO-2024073605-A2 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME PEPTIDREAM INC. (JP) 2024-04-04 WO disclosed
EP-0647449-A1 Sustained-release preparation of anti-endothelin substance Takeda Chemical Industries, Ltd. (JP) 1995-04-12 EP disclosed
EP-0626174-A2 Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-30 EP disclosed
EP-0552417-A1 Cyclic peptides and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0528312-A2 Cyclic peptides and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-02-24 EP disclosed
US-5116730-A AMINO ACID SUBSTITUTED 4-AMINOPHENAZONES FOR MEASURING ENZYME ACTIVITY BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1992-05-26 US disclosed
US-5081259-A Novel amino acid substituted 4-aminophenazones for measuring enzyme activity ABBOTT LABORATORIES (US) 1992-01-14 US disclosed
EP-0346870-A2 Novel amino acid substituted 4-aminophenazones for measuring enzyme activity THE BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) 1989-12-20 EP disclosed
US-4801721-A Stereospecific synthesis of carboxyalkyl peptides RYAN JAMES W (US) 1989-01-31 US disclosed
US-4603107-A SIMUTANEOUSLY REACTING WITH GLUTAMYLARYLAMIDE, THEN OXIDIZER AND COUPLING AGENT TO GIVE COLORED COMPOUND BOEHRINGER MANNHEIM GMBH (DE) 1986-07-29 US disclosed
EP-0103823-A2 Method and reagent for the determination of gamma-glutamyltransferase Roche Diagnostics GmbH (DE) 1984-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528808-B2 Therapy for erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) ABCC3, ABCC2, ABCB7 LTA4H 2245/4885L3MBTL1 980/4885SLC1A3 871/4885
US-20260098061-A1 EPHA2-BINDING PENDING PEPTIDE AND COMPOSITION COMPRISING SAME EPHA2, EPHA1, EPHB1 LTA4H 3838/4885L3MBTL1 250/4885SLC1A3 730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.