Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 7/20 | 1.00 |
| ▸ | CNR1 | P21554 | 6/20 | 1.00 |
| ▸ | RECQL | P46063 | 4/20 | 1.00 |
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 5/20 | 0.91 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.91 |
| ▸ | BLM | P54132 | 1/20 | 0.91 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.91 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17681378 | 0.95 | MAPT (1.00) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL17681379 | 0.92 | MEN1 (0.84) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15113525 | 0.88 | KMT2A (0.78) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15113174 | 0.88 | ALDH1A1 (0.78) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15113159 | 0.86 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15113203 | 0.84 | KMT2A (0.73) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15116289 | 0.81 | CYP3A4 (0.75) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL17681381 | 0.81 | MAPT (0.79) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15113243 | 0.81 | MEN1 (0.67) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL15113512 | 0.80 | KMT2A (0.67) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2019-07-16 | — | — | US | claimed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | claimed |
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-10076529-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2018-09-18 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-9315464-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | NANT HOLDINGS IP, LLC (US) | 2016-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10076529-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | RNGTT, MED23, MED25 | MEN1 4837/4885KMT2A 534/4885ALDH1A1 3512/4885 |
| US-10350225-B1 | Small molecule inhibitors of influenza A RNA-dependent RNA polymerase | RNGTT, MED23, MED25 | MEN1 4837/4885KMT2A 534/4885ALDH1A1 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.