Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | CTRC | Q99895 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9523272 | 0.98 | KDM4E (0.60) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9752787 | 0.93 | POLB (0.63) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9752676 | 0.88 | POLB (0.58) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL1240350 | 0.86 | MAPT (0.56) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16881026 | 0.86 | POLB (0.56) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4591947 | 0.86 | POLB (0.61) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16891528 | 0.84 | MAPT (0.61) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16246832 | 0.84 | POLB (0.54) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17457935 | 0.84 | POLB (0.54) | POLBNPSR1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16891381 | 0.84 | POLB (0.54) | POLBNPSR1KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768675-B1 | NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2026-04-01 | — | — | EP | claimed |
| EP-3365337-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | Selvita S.A. (PL) | 2018-08-29 | — | — | EP | claimed |
| WO-2017068064-A1 | PYRIDONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | SELVITA S.A. (PL) | 2017-04-27 | — | — | WO | claimed |
| EP-0888349-B1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2002-05-22 | — | — | EP | claimed |
| EP-0888349-A1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION | Novartis AG (CH) | 1999-01-07 | — | — | EP | claimed |
| WO-1997027199-A1 | PYRROLOPYRIMIDINES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | claimed |
| US-20260132149-A1 | Bridged Cyclic 5-Amino-6,8-Dihydro-1H-Furo[3,4-D]Pyrrolo[3,2-B]Pyridine-2-Carboxamide Compounds, Compositions Thereof, and Methods of Treatment Therewith | BEONE MEDICINES I GMBH (CH) | 2026-05-14 | — | — | US | disclosed |
| CN-116082237-B | Nitrogen-containing heterocyclic compound and preparation method thereof | 安徽中医药大学 | 2025-04-22 | — | — | CN | disclosed |
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | NOVARTIS AG (CH) | 2024-07-25 | — | — | US | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |
| CN-116082237-A | Nitrogen-containing heterocyclic compound and preparation method thereof | 安徽中医药大学 | 2023-05-09 | — | — | CN | disclosed |
| US-20220204838-A1 | LONG-AFTERGLOW LUMINESCENT MATERIAL | FUDAN UNIVERSITY (CN) | 2022-06-30 | — | — | US | disclosed |
| US-20220185778-A1 | PROLYL HYDROXYLASE INHIBITORS | AERPIO THERAPEUTICS INC (US) | 2022-06-16 | — | — | US | disclosed |
| EP-0572450-B1 | AZO DYES HAVING A DIAZO COMPONENT FROM THE AMINOBENZOPHENONE SERIES, AS WELL AS BISULPHONATED PYRIDONE COMPOUNDS | BASF AG (DE) | 1994-10-26 | — | — | EP | disclosed |
| WO-1991002721-A1 | 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-03-07 | — | — | WO | disclosed |
| EP-0406656-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-01-09 | — | — | EP | disclosed |
| US-4695565-A | Antibacterial 7β-heterocyclic-cephem | MERCK & CO., INC. (US) | 1987-09-22 | — | — | US | disclosed |
| EP-0177897-A2 | Antibacterial 7beta-heterocyclic-cephem | MERCK & CO. INC. (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4104273-A | Derivatives of 3-cyano-pyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4028084-A | Derivatives of 3-carboxy pyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245670-A1 | DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES | IKZF1, IKZF2, IKZF3 | POLB 1858/4885NPSR1 4487/4885KDM4E 345/4885 |
| US-20220185778-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, HIF1A, EGLN2 | POLB 2712/4885NPSR1 1640/4885KDM4E 249/4885 |
| US-20260132149-A1 | Bridged Cyclic 5-Amino-6,8-Dihydro-1H-Furo[3,4-D]Pyrrolo[3,2-B]Pyridine-2-Carboxamide Compounds, Compositions Thereof, and Methods of Treatment Therewith | MECP2, PRMT5, DNMT1 | POLB 334/4885NPSR1 4853/4885KDM4E 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.