Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932944 | 0.91 | POLB (0.50) | POLBNPSR1MAPK14EGLN1PSMB1 | |
| SCHEMBL30799185 | 0.88 | POLB (0.50) | POLBNPSR1MAPK14EGLN1KDM4E | |
| SCHEMBL14611520 | 0.88 | MAPT (0.57) | POLBNPSR1KDM4EALDH1A1TP53 | |
| SCHEMBL28003373 | 0.88 | EGLN1 (0.61) | POLBNPSR1EGLN1KDM4EALDH1A1 | |
| SCHEMBL28003659 | 0.88 | SMN1; SMN2 (0.50) | POLBNPSR1MAPK14KDM4E | |
| SCHEMBL1768170 | 0.88 | POLB (0.61) | POLBNPSR1MAPK14KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9523272 | 0.86 | KDM4E (0.60) | POLBNPSR1MAPK14KDM4EALDH1A1 | |
| SCHEMBL9752787 | 0.85 | POLB (0.63) | POLBNPSR1MAPK14EGLN1KDM4E | |
| SCHEMBL28224155 | 0.84 | NCF1 (0.60) | POLBNPSR1KDM4EALDH1A1TP53 | |
| SCHEMBL28817529 | 0.84 | MAPT (0.63) | POLBNPSR1KDM4EALDH1A1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |