Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 13/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 13/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682306 | 0.88 | CYP11B2 (0.36) | CYP11B2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL17682133 | 0.77 | — | — | |
| SCHEMBL18175106 | 0.67 | NPC1 (0.50) | — | |
| SCHEMBL18175072 | 0.66 | PDE4A (0.36) | — | |
| SCHEMBL19301625 | 0.63 | MAPK14 (0.43) | CYP11B2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL18256009 | 0.63 | — | — | |
| SCHEMBL19607693 | 0.62 | CYP11B2 (0.43) | CYP11B2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL20105842 | 0.61 | CYP11B2 (0.42) | CYP11B2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3017621 | 0.60 | MAPK13 (0.41) | CYP11B2MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL3012083 | 0.60 | MAPK13 (0.41) | CYP11B2MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054971-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | 南京明德新药研发股份有限公司 | 2016-04-14 | — | — | WO | disclosed |