Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16254142 | 0.85 | HPGD (0.38) | HPGDTSHRALDH1A1ATM | |
| SCHEMBL16254145 | 0.80 | ALDH1A1 (0.43) | HPGDTSHRCYP3A4MAPTUSP2 | |
| SCHEMBL17682243 | 0.79 | ALDH1A1 (0.35) | HPGDTSHRALDH1A1PTGS1PPARG | |
| SCHEMBL16254138 | 0.75 | HPGD (0.32) | HPGDTSHRPTGS1PPARGOPRK1 | |
| SCHEMBL17682184 | 0.74 | TSHR (0.31) | HPGDTSHR | |
| SCHEMBL16309384 | 0.73 | HPGD (0.33) | HPGDTSHR | |
| SCHEMBL16254156 | 0.70 | LMNA (0.46) | HPGDTSHRCYP3A4MAPTLMNA | |
| SCHEMBL15861026 | 0.70 | ALDH1A1 (0.37) | HPGDTSHRALDH1A1ATM | |
| SCHEMBL12197494 | 0.68 | ALDH1A1 (0.41) | HPGDTSHRCYP3A4MAPTUSP2 | |
| SCHEMBL16309643 | 0.68 | HPGD (0.30) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676676-B2 | Selective olefin metathesis with cyclometalated ruthenium complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160185684-A1 | SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | ZFR, ZDHHC7, ORC3 | HPGD 3713/4885TSHR 3394/4885CYP3A4 47/4885 |
| US-20160185684-A1 | SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES | ZDHHC7, COASY, ZDHHC2 | HPGD 2963/4885TSHR 4341/4885CYP3A4 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.