Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.55 |
| ▸ | SCN1A | P35498 | 2/20 | 0.55 |
| ▸ | SCN4A | P35499 | 2/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768241 | 0.89 | SCN8A (0.48) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL1768437 | 0.86 | SCN8A (0.66) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL1768416 | 0.82 | CYP1A2 (0.51) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL11896995 | 0.81 | SCN8A (0.51) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL11896994 | 0.81 | SCN8A (0.67) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL1768502 | 0.81 | CYP1A2 (0.48) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL11896968 | 0.80 | CYP1A2 (0.65) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL12649131 | 0.80 | SCN8A (0.65) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| Ammonia Solution, Strong SCHEMBL1768336 | 0.79 | CYP1A2 (0.64) | SCN8ASCN1ASCN4ASCN5ASCN9A | |
| SCHEMBL12648966 | 0.79 | SCN8A (0.76) | SCN8ASCN1ASCN4ASCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061469-A1 | INDAZOLE DERIVATIVES AND THEIR USE FOR BLOCKADING VOLTAGE DEPENDENT SODIUM CHANNELS | UNIVERSITY COLLEGE LONDON (GB) | 2011-05-26 | — | — | WO | disclosed |