Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17544553 | 0.94 | MMP13 (0.40) | MMP13GNRHRAGTR1AGTR2CES2 | |
| SCHEMBL17680451 | 0.91 | GNRHR (0.38) | MMP13GNRHRAGTR1AGTR2PDE6D | |
| SCHEMBL17544846 | 0.89 | MMP13 (0.42) | MMP13AGTR1AGTR2CES2PDE6D | |
| SCHEMBL17544535 | 0.88 | PDE6D (0.42) | MMP13AGTR1AGTR2CES2PDE6D | |
| SCHEMBL17670499 | 0.85 | MMP13 (0.40) | MMP13AGTR1AGTR2CES2PDE6D | |
| SCHEMBL17670353 | 0.85 | MMP13 (0.40) | MMP13AGTR1AGTR2CES2TP53 | |
| SCHEMBL17544971 | 0.85 | ALDH1A1 (0.44) | MMP13GNRHRAGTR1AGTR2CES2 | |
| SCHEMBL17670366 | 0.85 | MMP13 (0.40) | MMP13AGTR1AGTR2PDE6D | |
| SCHEMBL17549916 | 0.85 | MMP13 (0.39) | MMP13GNRHRAGTR1AGTR2CES2 | |
| SCHEMBL17680457 | 0.85 | MMP13 (0.40) | MMP13AGTR1AGTR2CES2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160102096-A1 | COMPOUNDS AND METHODS FOR INHIBITING HISTONE DEMETHYLASES | EPITHERAPEUTICS APS | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102096-A1 | COMPOUNDS AND METHODS FOR INHIBITING HISTONE DEMETHYLASES | PHF8, KDM3A, PHF2 | MMP13 397/4885GNRHR 2787/4885AGTR1 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.