SCHEMBL1768477

SCHEMBL1768477

Cc1cccc(Br)c1-c1ccccc1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
MAPK1 P28482 1/20 0.44
MYC P01106 1/20 0.42
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39
PBRM1 Q86U86 1/20 0.39
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
CA7 P43166 2/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDK2 Q15119 2/20 0.38
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31264394 0.93 ALDH1A1 (0.56) ALDH1A1MAOAMAOBMAPK1MYC
SCHEMBL10468391 0.91 ALDH1A1 (0.54) ALDH1A1MAOAMAOBMAPK1MYC
SCHEMBL28158900 0.85 ALDH1A1 (0.48) ALDH1A1MAOAMAOBMAPK1MYC
SCHEMBL28171115 0.84 ALDH1A1 (0.56) ALDH1A1MAOAMAOBMAPK1MYC
SCHEMBL1768545 0.83 ALDH1A1 (0.55) ALDH1A1MAOAMAOBMAPK1TSHR
SCHEMBL4537402 0.83 ALDH1A1 (0.60) ALDH1A1MAOAMAOBMAPK1MYC
SCHEMBL29803148 0.83 ALDH1A1 (0.55) ALDH1A1MAOAMAOBMAPK1TSHR
SCHEMBL10177314 0.81 ALDH1A1 (0.47) ALDH1A1MAOAMAOBMAPK1MYC
SCHEMBL10177310 0.81 ALDH1A1 (0.43) ALDH1A1MAOAMAOBMAPK1CA1
SCHEMBL3563744 0.78 ALDH1A1 (0.62) ALDH1A1MAOAMAOBMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011061439-A1 CATALYTIC PHOSPHINATION METHOD UNIVERSITE DE STRASBOURG (FR) 2011-05-26 WO disclosed