⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5608424 | 1.00 | — | — | |
| SCHEMBL14400415 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL9784814 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL13657791 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL14668319 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL18557198 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL284632 | 0.80 | ALDH1A1 (0.50) | — | |
| SCHEMBL11474705 | 0.80 | — | — | |
| SCHEMBL1014010 | 0.80 | ALDH1A1 (0.50) | — | |
| SCHEMBL17663536 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045043-B1 | EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE | RELMADA THERAPEUTICS INC (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-3045043-A1 | EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE | Relmada Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| EP-2448406-B1 | EXTENDED RELEASE ORAL PHARMACEUTICAL COMPOSITIONS OF 3-HYDROXY-N-METHYLMORPHINAN AND METHOD OF USE | RELMADA THERAPEUTICS INC (US) | 2016-04-20 | — | — | EP | disclosed |