Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1345129 | 0.86 | KDM4E (0.52) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL29206869 | 0.84 | KDM4E (0.56) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL11529406 | 0.84 | NAALAD2 (0.50) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL26061311 | 0.83 | KDM4E (0.45) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL29065914 | 0.82 | TDP1 (0.54) | KDM4ETHRBKMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL31279551 | 0.81 | NAALAD2 (0.48) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL23682363 | 0.79 | NAALAD2 (0.44) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL28204810 | 0.79 | THRB (0.52) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL13168811 | 0.79 | NAALAD2 (0.46) | KDM4ETHRBKMT2AALDH1A1CYP1A2 | |
| SCHEMBL10076899 | 0.78 | KDM4E (0.74) | KDM4EALDH1A1CYP2D6TSHRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203098-A1 | HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE | JCR PHARMACEUTICALS CO., LTD. (JP) | 2023-06-29 | — | — | US | disclosed |
| CN-110256297-A | A kind of preparation method of N-Boc- (R) -2- amino -4,4- dimethyl valeric acid | 爱斯特（成都）生物制药股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| EP-3274361-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2018-01-31 | — | — | EP | disclosed |
| WO-2016150576-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2016-09-29 | — | — | WO | disclosed |
| EP-2978771-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor Ag (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978772-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | Polyphor AG (CH) | 2016-02-03 | — | — | EP | disclosed |
| EP-2970243-A2 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014161782-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014161781-A1 | BETA-HAIRPIN PEPTIDOMIMETICS | POLYPHOR AG (CH) | 2014-10-09 | — | — | WO | disclosed |
| WO-2014144100-A2 | SGC STIMULATORS | NAKAI TAKASHI (US) | 2014-09-18 | — | — | WO | disclosed |
| CN-102844327-A | Template-fixed peptidomimetics with CXCR7 modulatory activity | POLYPHOR AG | 2012-12-26 | — | — | CN | disclosed |
| CN-102712676-A | Template-fixed peptidomimetics with CCR10 antagonistic activty | POLYPHOR AG | 2012-10-03 | — | — | CN | disclosed |
| EP-2501715-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | Polyphor Ag (CH) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060937-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |
| CN-1384830-A | Novel spiroheterocyclic compounds as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMA (US) | 2002-12-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203098-A1 | HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE | TFRC, SLC3A2, SLC7A1 | KDM4E 3553/4885THRB 26/4885KMT2A 2608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.