Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 4/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13585045 | 0.89 | ALDH1A1 (0.34) | CHRM4ALDH1A1ACKR3METAP2APP | |
| SCHEMBL13585047 | 0.84 | ACE (0.35) | CHRM4ALDH1A1ACKR3METAP2APP | |
| SCHEMBL27872429 | 0.82 | CHRNB2 (0.34) | CHRM4ALDH1A1ACKR3CHRM3XPNPEP1 | |
| SCHEMBL1769501 | 0.75 | CHRNB2 (0.33) | ACKR3CHRM3 | |
| SCHEMBL27888847 | 0.75 | CHRNB2 (0.33) | ACKR3CHRM3 | |
| SCHEMBL13584651 | 0.74 | PMP22 (0.35) | ACKR3CHRM3 | |
| SCHEMBL27888818 | 0.74 | PMP22 (0.35) | ACKR3CHRM3 | |
| SCHEMBL25660550 | 0.73 | CYP1A2 (0.45) | CHRM3 | |
| SCHEMBL25662234 | 0.73 | CYP1A2 (0.45) | CHRM3 | |
| SCHEMBL1768754 | 0.70 | ACE (0.37) | CHRM4ALDH1A1ACKR3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501715-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | Polyphor Ag (CH) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011060937-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CCR10 ANTAGONISTIC ACTIVTY | POLYPHOR AG (CH) | 2011-05-26 | — | — | WO | disclosed |