Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732279 | 0.88 | GRIN2D (0.44) | PTPRASMN1; SMN2FDPSPRSS1PRSS2 | |
| SCHEMBL29058174 | 0.88 | GRIN2D (0.44) | PTPRASMN1; SMN2FDPSPRSS1PRSS2 | |
| SCHEMBL21770640 | 0.88 | GRIN2D (0.44) | PTPRASMN1; SMN2FDPSPRSS1PRSS2 | |
| SCHEMBL23844725 | 0.85 | KCNH2 (0.42) | PTPRASMN1; SMN2LPAR3FDPSPRSS1 | |
| SCHEMBL18647910 | 0.85 | KCNH2 (0.42) | PTPRASMN1; SMN2LPAR3FDPSPRSS1 | |
| SCHEMBL2130533 | 0.82 | PTPRA (0.55) | PTPRAHDAC6HDAC1SMN1; SMN2CYP1A2 | |
| SCHEMBL28265189 | 0.82 | GRIN2D (0.46) | PTPRACYP1A2CYP2C19FDPS | |
| SCHEMBL21879789 | 0.81 | CPA3 (0.55) | HDAC6HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL18948136 | 0.79 | GRIN2D (0.44) | PTPRACYP1A2CYP2C19FDPS | |
| Dimethylamine SCHEMBL20994614 | 0.77 | HDAC3 (0.52) | HDAC6HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209644-B1 | HETEROCYCLIC AMPHOTERIC COMPOUNDS AS SURFACTANTS | EASTMAN CHEM CO (US) | 2019-09-18 | — | — | EP | disclosed |
| US-9822073-B2 | Heterocyclic amphoteric compounds | EASTMAN CHEMICAL COMPANY (US) | 2017-11-21 | — | — | US | disclosed |
| EP-3209644-A1 | HETEROCYCLIC AMPHOTERIC COMPOUNDS AS SURFACTANTS | Eastman Chemical Company (US) | 2017-08-30 | — | — | EP | disclosed |
| US-20170022159-A1 | HETEROCYCLIC AMPHOTERIC COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2017-01-26 | — | — | US | disclosed |
| US-9533951-B2 | Heterocyclic amphoteric compounds | EASTMAN CHEMICAL COMPANY (US) | 2017-01-03 | — | — | US | disclosed |
| US-20160107994-A1 | HETEROCYCLIC AMPHOTERIC COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160107994-A1 | HETEROCYCLIC AMPHOTERIC COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AQP4, PLEC | PTPRA 4299/4885HDAC6 138/4885HDAC1 249/4885 |
| US-20170022159-A1 | HETEROCYCLIC AMPHOTERIC COMPOUNDS | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PLEC, H1-4 | PTPRA 4238/4885HDAC6 161/4885HDAC1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.