Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 10/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.56 |
| ▸ | GRM8 | O00222 | 1/20 | 0.51 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11250845 | 0.99 | LTA4H (0.59) | LTA4HKDM4CGRM8GRM4HSD17B10 | |
| SCHEMBL30502422 | 0.87 | LTA4H (0.65) | LTA4HHSD17B10KDM4EALDH1A1CASR | |
| SCHEMBL7039236 | 0.86 | LTA4H (0.60) | LTA4HALDH1A1CASR | |
| SCHEMBL6006561 | 0.85 | LTA4H (0.59) | LTA4HKDM4EALDH1A1CASRPOLB | |
| SCHEMBL10599992 | 0.83 | LTA4H (0.59) | LTA4HALDH1A1HPGDCASRPOLB | |
| SCHEMBL176775 | 0.82 | LTA4H (0.55) | LTA4HKDM4CCASRTDP1 | |
| SCHEMBL11574416 | 0.82 | LTA4H (0.55) | LTA4HCASR | |
| SCHEMBL14586345 | 0.81 | LTA4H (0.54) | LTA4HGRM8GRM4ALDH1A1 | |
| SCHEMBL1870730 | 0.81 | LTA4H (0.54) | LTA4HGRM8GRM4ALDH1A1 | |
| SCHEMBL29355173 | 0.81 | LTA4H (0.54) | LTA4HGRM8GRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336331-A | Method for assaying the activity of γ-glutamyl transpeptidase in serum | NITTO BOSEKI CO., LTD. (JP) | 1982-06-22 | — | — | US | claimed |
| US-4281181-A | SUBSTRATE FOR ASSAYING GLUTAMYL TRANSPEPTIDASE | NITTO BOSEKI CO., LTD. (JP) | 1981-07-28 | — | — | US | claimed |
| JP-56023897-A | — | — | None | — | — | JP | disclosed |
| JP-59232099-A | — | — | None | — | — | JP | disclosed |
| EP-2345636-B1 | CASR AGONIST | AJINOMOTO KK (JP) | 2016-03-30 | — | — | EP | disclosed |
| US-9174932-B2 | CaSR agonists | AJINOMOTO CO., INC. (JP) | 2015-11-03 | — | — | US | disclosed |
| US-9000208-B2 | Glutamate derivatives or salts thereof | AJINOMOTO CO., INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8877739-B2 | Prophylactic agent or therapeutic agent for diabetes or obesity | AJINOMOTO CO., INC. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20140303122-A1 | CASR AGONISTS | AJINOMOTO CO., INC. (JP) | 2014-10-09 | — | — | US | disclosed |
| US-8796485-B2 | CaSR agonists | AJINOMOTO CO., INC. (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20130102570-A1 | PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DIABETES OR OBESITY | AJINOMOTO CO., INC. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20110251418-A1 | CASR AGONISTS | AJINOMOTO CO., INC. (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2345636-A1 | CASR AGONIST | Ajinomoto Co., Inc. (JP) | 2011-07-20 | — | — | EP | disclosed |
| JP-S59232099-A | DETERMINATION OF ENZYMATIC ACTIVITY | KYOWA MEDETSUKUSU KK | 1984-12-26 | — | — | JP | disclosed |
| US-4336331-A | Method for assaying the activity of γ-glutamyl transpeptidase in serum | NITTO BOSEKI CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| US-4336331-A | Method for assaying the activity of γ-glutamyl transpeptidase in serum | NITTO BOSEKI CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| US-4281181-A | SUBSTRATE FOR ASSAYING GLUTAMYL TRANSPEPTIDASE | NITTO BOSEKI CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4281181-A | SUBSTRATE FOR ASSAYING GLUTAMYL TRANSPEPTIDASE | NITTO BOSEKI CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4281181-A | SUBSTRATE FOR ASSAYING GLUTAMYL TRANSPEPTIDASE | NITTO BOSEKI CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |
| JP-S5623897-A | MEASUREMENT OF GAMMA-GTP ACTIVITY BY USING NOVEL SUBSTRATE | YATORON:KK | 1981-03-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303122-A1 | CASR AGONISTS | CASR, GIPR, GRIK5 | LTA4H 2221/4885KDM4C 4513/4885GRM8 86/4885 |
| US-20130102570-A1 | PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DIABETES OR OBESITY | GPR119, GIPR, CASR | LTA4H 1419/4885KDM4C 4860/4885GRM8 934/4885 |
| US-20110251418-A1 | CASR AGONISTS | CASR, GIPR, GRIK5 | LTA4H 2221/4885KDM4C 4513/4885GRM8 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.