Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.34 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31534727 | 0.82 | PTGS2 (0.40) | PTGS2KDM4ELMNARORCDDR1 | |
| SCHEMBL17422537 | 0.82 | PTGS2 (0.40) | PTGS2KDM4ELMNARORCDDR1 | |
| SCHEMBL29679797 | 0.82 | PTGS2 (0.40) | PTGS2KDM4ELMNARORCDDR1 | |
| SCHEMBL21578031 | 0.81 | DDR1 (0.37) | PTGS2KDM4EDDR1COMTCNR2 | |
| SCHEMBL15933507 | 0.80 | PTGS2 (0.41) | PTGS2DDR1COMTCNR2MEN1 | |
| SCHEMBL29431633 | 0.80 | PTGS2 (0.41) | PTGS2DDR1COMTCNR2MEN1 | |
| SCHEMBL14677191 | 0.80 | RORC (0.39) | PTGS2RORCDDR1 | |
| SCHEMBL19840538 | 0.78 | TRPV1 (0.37) | PTGS2DDR1COMTNR1H2 | |
| SCHEMBL21805952 | 0.78 | HSD17B10 (0.33) | KDM4EDDR1KMT2A | |
| SCHEMBL22280385 | 0.78 | DDR1 (0.35) | RORCDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016058928-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-21 | — | — | WO | disclosed |
| WO-2016058928-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-21 | — | — | WO | disclosed |