Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL11074140 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10TDP1LMNA | |
| SCHEMBL1330344 | 0.82 | — | — | |
| SCHEMBL523 | 0.82 | — | — | |
| SCHEMBL1331774 | 0.82 | — | — | |
| SCHEMBL9866292 | 0.82 | — | — | |
| SCHEMBL5305593 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TSHRHSD17B10TDP1CA1 | |
| SCHEMBL1331977 | 0.82 | — | — | |
| Acetic Acid Methyl Ester SCHEMBL16060055 | 0.80 | — | — | |
| SCHEMBL3957549 | 0.78 | — | — | |
| SCHEMBL4535189 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348460-A | Preparation method of BTK degradation agent | 四川海思科制药有限公司 | 2023-06-27 | — | — | CN | claimed |
| CN-116323594-A | Preparation method of BTK degradation agent | 四川海思科制药有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-113321643-B | Intermediate, preparation method and application thereof in synthesizing vincamine | 四川大学 | 2023-06-20 | — | — | CN | claimed |
| CN-113402506-B | Intermediate, preparation method and application thereof in synthesizing vinca-bunting | 四川大学 | 2023-06-16 | — | — | CN | claimed |
| CN-101177446-B | Novel method for stereo-selective chemosynthesis of drospirenone | SHANGHAI DRUG INST CHINESE ACADEMY OF SCIENCES | 2011-06-15 | — | — | CN | claimed |
| CN-100424089-C | Method for preparing macrolides half-synthesized antibiotics telithromycin | UNIV CHINA PHARMA (CN) | 2008-10-08 | — | — | CN | claimed |
| CN-101177446-A | Novel method for stereo-selective chemosynthesis of drospirenone | SHANGHAI DRUG INST CHINESE ACA (CN) | 2008-05-14 | — | — | CN | claimed |
| CN-1800198-A | Method for preparing macrolides half-synthesized antibiotics telithromycin | UNIV CHINA PHARMA (CN) | 2006-07-12 | — | — | CN | claimed |
| US-4491659-A | 2,6-Didioxy-3-amine,4-carboxy methylglycoside and related compounds | MERCK & CO., INC. (US) | 1985-01-01 | — | — | US | claimed |
| EP-0040913-B1 | 23-KETO DERIVATIVES OF C-076 COMPOUNDS, THEIR PREPARATION AND ANTI-PARASITIC USE | MERCK & CO. INC. (US) | 1984-07-25 | — | — | EP | claimed |
| EP-0040913-A1 | 23-Keto derivatives of C-076 compounds, their preparation and anti-parasitic use | MERCK & CO. INC. (US) | 1981-12-02 | — | — | EP | claimed |
| CN-118284645-A | Polyethylene glycol lipid containing lysine nucleus | 厦门赛诺邦格生物科技股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115197078-B | Pegylated lipid and modified liposome thereof, pharmaceutical composition containing liposome and preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024067816-A1 | PEGYLATED LIPID CONTAINING LYSINE CORE | 厦门赛诺邦格生物科技股份有限公司 | 2024-04-04 | — | — | WO | disclosed |
| CN-117510830-A | Pegylated lipid and modified liposome thereof, pharmaceutical composition containing liposome and preparation and application of pharmaceutical composition | 厦门赛诺邦格生物科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-4119577-A | Substituted-norbornane perfumes compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4113873-A | 8-AZAPROSTANOIC ACID DERIVATIVES | TANABE SEIYAKU CO. LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4076853-A | Flavoring with substituted norbornane derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-3962217-A | Process for the manufacture of Δ16 -steroid-14β,18,20-triols and -14β,20-diol-18-ols of the pregnane series | CIBA-GEIGY CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
| US-3941796-A | α-(Hydroxy and alkoxy substituted)phenyl-α-(2-piperidinyl)-methanols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-03-02 | — | — | US | disclosed |