Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 16/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.65 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276042 | 0.96 | HRH3 (0.65) | ACP1HRH3SMARCA2 | |
| SCHEMBL491641 | 0.85 | ACP1 (0.70) | ACP1HRH3SMARCA2 | |
| SCHEMBL20552777 | 0.85 | ACP1 (0.58) | ACP1HRH3 | |
| SCHEMBL20552916 | 0.85 | ACP1 (0.58) | ACP1HRH3 | |
| SCHEMBL2512341 | 0.82 | ACP1 (0.55) | ACP1 | |
| SCHEMBL20552524 | 0.82 | HRH3 (0.55) | ACP1HRH3 | |
| SCHEMBL20553037 | 0.82 | HRH3 (0.55) | ACP1HRH3 | |
| SCHEMBL5281506 | 0.82 | ACP1 (0.66) | ACP1HRH3 | |
| SCHEMBL17688792 | 0.81 | ACP1 (1.00) | ACP1SMARCA2 | |
| SCHEMBL491669 | 0.81 | HRH3 (0.66) | ACP1HRH3SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11220486-B2 | Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY (US) | 2022-01-11 | — | — | US | disclosed |
| US-11220486-B2 | Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY (US) | 2022-01-11 | — | — | US | disclosed |
| EP-3206689-B1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE AND USES THEREOF | LA JOLLA INST OF ALLERGY & IMMUNOLOGY (US) | 2021-12-08 | — | — | EP | disclosed |
| EP-3206689-B1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE AND USES THEREOF | LA JOLLA INST OF ALLERGY & IMMUNOLOGY (US) | 2021-12-08 | — | — | EP | disclosed |
| US-20200290977-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2020-09-17 | — | — | US | disclosed |
| US-20200290977-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2020-09-17 | — | — | US | disclosed |
| US-10626094-B2 | Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-04-21 | — | — | US | disclosed |
| US-10626094-B2 | Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2020-04-21 | — | — | US | disclosed |
| US-20170247340-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2017-08-31 | — | — | US | disclosed |
| US-20170247340-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2017-08-31 | — | — | US | disclosed |
| US-20170247340-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY | 2017-08-31 | — | — | US | disclosed |
| EP-3206689-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE AND USES THEREOF | La Jolla Institute of Allergy & Immunology (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016061280-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE AND USES THEREOF | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY (US) | 2016-04-21 | — | — | WO | disclosed |
| WO-2016061280-A1 | INHIBITORS OF LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE AND USES THEREOF | LA JOLLA INSTITUTE OF ALLERGY & IMMUNOLOGY (US) | 2016-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11220486-B2 | Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof | ACP1, PTPRCAP, PTPA | ACP1 1/4885HRH3 4805/4885SMARCA2 3356/4885 |
| US-10626094-B2 | Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof | ACP1, PTPRCAP, PTPA | ACP1 1/4885HRH3 4805/4885SMARCA2 3356/4885 |
| US-20200290977-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | ACP1, PTPRCAP, PTPA | ACP1 1/4885HRH3 4805/4885SMARCA2 3356/4885 |
| US-20170247340-A1 | Inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase and Uses Thereof | ACP1, PTPRCAP, PTPA | ACP1 1/4885HRH3 4805/4885SMARCA2 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.