Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 10/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522515 | 0.87 | ACP1 (0.52) | ACP1SLC6A4DRD2HTR2AHRH1 | |
| SCHEMBL17688782 | 0.82 | ACP1 (0.68) | ACP1 | |
| SCHEMBL5276042 | 0.79 | HRH3 (0.65) | ACP1 | |
| SCHEMBL2486143 | 0.77 | HRH3 (0.70) | — | |
| SCHEMBL491641 | 0.74 | ACP1 (0.70) | ACP1 | |
| SCHEMBL7288986 | 0.73 | DRD4 (0.47) | SLC6A4DRD2SLC6A2 | |
| SCHEMBL2485055 | 0.72 | HRH3 (0.73) | — | |
| SCHEMBL28506410 | 0.71 | SLC2A1 (0.57) | HTR1AADRA1DADRA1AADRA1BSLC2A1 | |
| SCHEMBL2487986 | 0.71 | HRH3 (0.68) | — | |
| SCHEMBL5281506 | 0.71 | ACP1 (0.66) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379505-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | Designmedix, Inc. (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010065932-A1 | MODIFIED CHLOROQUINES WITH SINGLE RING MOIETY OR FUSED RING MOIETY | DESIGNMEDIX, INC. (US) | 2010-06-10 | — | — | WO | disclosed |