Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17277149 | 0.93 | APEX1 (0.44) | APEX1 | |
| SCHEMBL17277629 | 0.83 | APEX1 (0.59) | APEX1 | |
| SCHEMBL17834007 | 0.83 | APEX1 (0.59) | APEX1 | |
| SCHEMBL17689293 | 0.80 | APEX1 (0.55) | APEX1 | |
| SCHEMBL17277148 | 0.76 | APEX1 (0.57) | APEX1 | |
| SCHEMBL17689291 | 0.74 | APEX1 (0.75) | APEX1 | |
| SCHEMBL19821304 | 0.71 | EPHX2 (0.42) | — | |
| SCHEMBL17689292 | 0.69 | APEX1 (0.57) | APEX1 | |
| SCHEMBL15711325 | 0.68 | APEX1 (0.51) | APEX1 | |
| SCHEMBL17277627 | 0.68 | APEX1 (0.72) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315481-B2 | Compounds and methods for treating leukemia | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-04-19 | — | — | US | disclosed |