Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 1/20 | 0.60 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA3 | P07451 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760213 | 0.96 | EEF2K (0.60) | EEF2KPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14544487 | 0.82 | SMN1; SMN2 (0.63) | ALDH1A1CYP3A4PTGS2PTGS1KMT2A | |
| SCHEMBL14227519 | 0.77 | EEF2K (0.55) | EEF2KPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL17689396 | 0.77 | PTGS2 (0.47) | ALDH1A1PTGS2PTGS1CA1CA2 | |
| SCHEMBL14242974 | 0.77 | EEF2K (0.55) | EEF2KPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19558567 | 0.74 | SMN1; SMN2 (0.62) | ALDH1A1CYP3A4PTGS2PTGS1KMT2A | |
| SCHEMBL1463591 | 0.73 | EEF2K (0.55) | EEF2KPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16099469 | 0.72 | CA2 (0.45) | EEF2KALDH1A1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL1783083 | 0.69 | EEF2K (0.50) | EEF2KPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11639128 | 0.69 | EEF2K (0.50) | EEF2KPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315454-B2 | Compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-04-19 | — | — | US | disclosed |